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What is the (Secret) Key to our Physiological Harmony? The Endocannabinoid System

Is the effect of CBD a “miracle”? No.

But there is, actually, something magical about how this natural substance works: the endocannabinoid system.

The Unique Relationship Between CBD & Our Bodies

CBD has been in the spotlight these last years for the wide range of positive effects people experience from it. It’s used for everything from sleep and anxiety to pain. But how is it that a single compound can have such an extensive impact?

It’s owed to a neuromodulatory system we all carry, namely, the Endocannabinoid System (ECS). It’s best known for its vital role in aligning and harmonizing the various complex nervous systems altogether, ultimately, achieving homeostasis.

In other words, the Endocannabinoid System is what keeps our minds and bodies in balance. It sets in when something is “out of whack”; if you are experiencing an abnormal sensation of pain, your body activates the Endocannabinoid System to set things right again.

Not only pain, but the ECS plays a crucial role in the management of stress, appetite, sleep, mood, hormones, learning, memory, immune function, reward centers and much more. It is not for nothing that we have used this plant for over 7,000 years.

But like everything else, the Endocannabinoid System can underperform, and there’s even a name for that: Clinical Endocannabinoid Deficiency.

This is where CBD products could help improve balance.

We need the Endocannabinoid System to function optimally because it is the key to maintaining physiological balance.

What is the connection between the ECS and Cannabis plants such as hemp?

Our own bodies produce endocannabinoids (“endo” is Greek for “inside”). The most researched endocannabinoids are 2-AG and anandamide.

The Cannabis Sativa L plant, on the other hand, contains phytocannabinoids (“phyto” is Greek for “plant”). The most studied of these are CBD, THC and CBG.

Endo- and phytocannabinoids share a very similar molecular structure and thus interact significantly: CBD (Cannabidiol), for example, is able to stimulate the production of endocannabinoids.

The simple explanation for the common name is that our Endocannabinoid Systems were discovered through research on the phytocannabinoids in Cannabis, a groundbreaking discovery made in the late 1980s.

Why haven’t we heard anything about it since its discovery in the 1980s?

The Endocannabinoid System is undoubtedly fascinating. 

So, why is it that such a fundamental physiological system doesn’t share the same pages with other well-known bodily functions in our biology books? Even in medical schools or universities, it’s rarely taught. 

In terms of reputation, Cannabis’ potential psychoactive effects have long trumped the plant’s therapeutic potential, limiting its clinical use. Some also argue that the plant was intentionally kept away from the public for political reasons.

Regardless, it is certainly unfortunate that we have limited our search for further groundbreaking knowledge about this revolutionary discovery because of a single psychoactive trait in a plant (which actually occurs only in a few strain varieties).

In most cases, hemp is not considered psychoactive at all. On the contrary, the plant probably contains at least one hundred more cannabinoids with therapeutic potential.

Fortunately, more and more countries are opening up to applications from hemp and cannabis, so we are optimistic that we will gradually give our endocannabinoid systems the attention they need.

After all, the ECS simply contributes to a better quality of life.

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What LAYV® users say

Catriona DumontCatriona Dumont
07:46 13 Jul 24
After a period of a lot of worrying, anxiety and especially panic attacks, the CBD 20% drops from LAYV really help me find some peace. 🙏🏻
Leonie BijlLeonie Bijl
07:11 13 Jun 24
Nice CBD oil, I take the 20% one for pain complaints and for a good night's sleep!
Jesse BlankendaalJesse Blankendaal
14:27 10 Jun 24
100% recommended if you are looking for A-quality CBD oil!
Carlos RosalCarlos Rosal
04:35 24 May 24
Since using this I notice that I have a better night's sleep, thank you!
ghm lammersghm lammers
20:13 12 May 24
Trustworthy !
Caspar de KlerCaspar de Kler
13:18 17 Apr 24
Top quality, good customer service
14:01 13 Mar 24
I bought the CBD oil on the recommendation of a friend who was very satisfied with it. I think it's a nice oil! I don't notice much of the effects, but I do sleep a little better since I started using it so I'm satisfied :)
Diewertje van BavelDiewertje van Bavel
20:41 07 Feb 24
Great product. It helps me with my pain and stress complaints. It also makes me sleep a lot better. I can really recommend this product!
Lilian DibbetsLilian Dibbets
16:28 15 Jan 24
This really is a fantastic product. I was always a good sleeper, but with this CBD oil (20%) I sleep much deeper and wake up rested. In addition, it helps to calm my nervous system and I am much calmer and focused throughout the day. I recommend this product to everyone for a calm nervous system and good health. Think of it as a nutritional supplement that should not be missing in this hectic Western world we live in.
Richard LemmensRichard Lemmens
10:44 18 Dec 23
What a fantastic product. For several months now we have been using the LAYV CBD variant 20% daily before going to sleep as a routine. As young parents, sleep is sacred to us, but with children this is sometimes lacking. By using the 20% variant, we both notice that we sleep much deeper, making us more rested in the morning.We also use the drug when we experience a stressful situation. By using a few drops, we quickly notice that we become calmer and can continue with our busy daily work lives.Previously used products from other brands, but these do not provide a pleasant mouthfeel and the taste is not as mild as the LAYV variant.
Fabiana FiniFabiana Fini
17:41 04 Dec 23
Liesbeth MekkeringLiesbeth Mekkering
10:14 14 Nov 23
I slept wonderfully thanks to LAYV, I couldn't live without it
Tahsin BulbulTahsin Bulbul
07:22 30 Oct 23
Juan Calixto morelloJuan Calixto morello
13:13 29 Oct 23
I recently no longer suffer from sleepless nights thanks to layv!
Nikos VasilatosNikos Vasilatos
17:19 25 Jun 23
Happy with the product, the responsiveness of the Layv team and the smooth delivery. Recommended!
Michal SokolowskiMichal Sokolowski
21:05 15 Jun 23
Excellent oils, quick contact if you have any questions, fast shipping abroad, I recommend! Greetings from Poland!
Charles PierrepontCharles Pierrepont
17:31 05 Apr 23
The LAYV CBD extract tastes and feels very clean. Dealing with the team at LAYV has been a pleasure. For someone who travels a lot, the clean CBD extract absolutely helps to unwind at the end of a long day.
Clare La Feber-ToolisClare La Feber-Toolis
06:24 30 Mar 23
I used the 5% LAYV CBD to manage pain from the symptoms of arthritis and it really helps. It has completely reduced the need for strong painkillers which is great. I also take a couple of drops of CBD if I feel stressed or overwhelmed and it calms me down. Highly recommend this CBD oil.
Runa WynekenRuna Wyneken
11:58 28 Sep 22
Love this product and the brand! Totally recommend it! Cleanest CBD out there!
Sven HurksSven Hurks
10:33 15 Jun 22
I have been using LAYV CBD for over one year, improving my sleep quality significantly.
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We (my wife and I) love this product. We use it to relax and unwind in the evening for a better night's sleep. We both noticed that our stress levels dropped significantly.....
Ferdinand van der Neut
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LAYV's CBD oil provides more structure to my thinking throughout the day. In the process, it greatly improves the quality of my sleep with just a few drops a day. Can't say anything but highly recommended!
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I really love this product! It helps me with anxiety, confidence, relaxation and pain relief. My advice would be to take a few drops every day so that it can be absorbed into the bloodstream and you can enjoy the long-term benefits. 1000% recommended!
Kas van Vliet
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Calming without the risk of paranoia. I used to reach for cannabis on very sporadic frequencies to unload from a busy existence as an entrepreneur and journalist, but smoking weed or hash was always a gamble for me: 50/50 chance of a slightly paranoid experience that exacerbated stress rather than reduced it. For me, this is a good substitute that allows me to relax physically and mentally, but sin negative high. But don't think of it as a panacea; you have to create a peaceful environment for it to really come into its own.
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I bought a bottle at Jumbo today, because I am always very cramped and tense, and suffer a lot from headaches and stress..... i must say i am pleasantly surprised, that t is sold by jumbo, and that t works! Definitely worth a try! Am curious if there will be more products from you.
H. Paulus de Groot
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Have been using this for months for chronic pain in my shoulder, and it just works!
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The product has a good taste despite its high concentration (500 mg). It helps me with stress, sleep and pain.
Willem Spoor
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Helps excellent against osteoarthritis pain
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Good product and good minty taste
J.A. Worskasan
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Layv Cbd oil makes me calmer, it helps me with livedo reticularis on my legs, after using it my legs become normal again. I used CBD from other brands and Layv Cbd oil is definitely the highest quality product.